CATH Domain 1fxhB01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.20	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
	3.60.20.10	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1

Domain Context

CATH Clusters

Superfamily	Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1
Functional Family

Enzyme Information

3.5.1.11

Penicillin amidase.

based on mapping to UniProt P06875

Penicillin + H(2)O = a carboxylate + 6-aminopenicillanate.

UniProtKB Entries (1)

PAC_ECOLX

Escherichia coli

Penicillin G acylase

PDB Structure

PDB	1FXH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies. Alkema, W.B., Hensgens, C.M., Kroezinga, E.H., de Vries, E., Floris, R., van der Laan, J.M., Dijkstra, B.W., Janssen, D.B. Protein Eng.