CATH Classification

Domain Context

CATH Clusters

Superfamily NADH:ubiquinone oxidoreductase-like, 20kDa subunit
Functional Family

Enzyme Information

1.12.2.1
Cytochrome-c3 hydrogenase.
based on mapping to UniProt P18187
H(2) + 2 ferricytochrome c3 = 2 H(+) + 2 ferrocytochrome c3.
-!- Some forms of the enzyme contain nickel ([NiFe]-hydrogenases) and, of these, some contain selenocysteine ([NiFeSe]-hydrogenases). -!- Methylene blue and other acceptors can also be reduced.

UniProtKB Entries (1)

P18188
PHNL_DESFR
Desulfovibrio fructosivorans
Periplasmic [NiFe] hydrogenase large subunit

PDB Structure

PDB 1FRF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
3Fe-4S] to [4Fe-4S] cluster conversion in Desulfovibrio fructosovorans [NiFe] hydrogenase by site-directed mutagenesis
Rousset, M., Montet, Y., Guigliarelli, B., Forget, N., Asso, M., Bertrand, P., Fontecilla-Camps, J.C., Hatchikian, E.C.
Proc.Natl.Acad.Sci.USA