CATH Domain 1fltW00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.90	Cystine Knot Cytokines, subunit B
	2.10.90.10	Cystine-knot cytokines

Domain Context

CATH Clusters

Superfamily	Cystine-knot cytokines
Functional Family	Vascular endothelial growth factor A

Enzyme Information

UniProtKB Entries (1)

VGFR1_HUMAN

Homo sapiens

Vascular endothelial growth factor receptor 1

PDB Structure

PDB	1FLT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Crystal structure at 1.7 A resolution of VEGF in complex with domain 2 of the Flt-1 receptor. Wiesmann, C., Fuh, G., Christinger, H.W., Eigenbrot, C., Wells, J.A., de Vos, A.M. Cell(Cambridge,Mass.)