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1 keywords

CATH Domain 1fe5A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.90 Phospholipase A2
Homologous Superfamily 1.20.90.10 Phospholipase A2 domain

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Acidic phospholipase A2

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt Q9DF52
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

Q9DF52
PA2B_BUNCE
Bungarus caeruleus
Basic phospholipase A2 KPA2

PDB Structure

PDB 1FE5
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Sequence and crystal structure determination of a basic phospholipase A2 from common krait (Bungarus caeruleus) at 2.4 A resolution: identification and characterization of its pharmacological sites.
Singh, G., Gourinath, S., Sharma, S., Paramasivam, M., Srinivasan, A., Singh, T.P.
J.Mol.Biol.
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