CATH Domain 1ezrC00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.245	Inosine-uridine Nucleoside N-ribohydrolase; Chain A
	3.90.245.10	Ribonucleoside hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonucleoside hydrolase-like
Functional Family	Inosine-uridine preferring nucleoside hydrolase

Enzyme Information

3.2.2.2	Inosine nucleosidase. based on mapping to UniProt P83851 Inosine + H(2)O = D-ribose + hypoxanthine.
3.2.2.3	Uridine nucleosidase. based on mapping to UniProt P83851 Uridine + H(2)O = D-ribose + uracil.

UniProtKB Entries (1)

IUNH_LEIMA

Leishmania major

Inosine-uridine preferring nucleoside hydrolase

PDB Structure

PDB	1EZR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Nucleoside hydrolase from Leishmania major. Cloning, expression, catalytic properties, transition state inhibitors, and the 2.5-a crystal structure. Shi, W., Schramm, V.L., Almo, S.C. J.Biol.Chem.