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CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Succinate--CoA ligase [ADP-forming] subunit alpha

Enzyme Information

6.2.1.4
Succinate--CoA ligase (GDP-forming).
based on mapping to UniProt O19069
GTP + succinate + CoA = GDP + phosphate + succinyl-CoA.
-!- Itaconate can act instead of succinate and ITP instead of GTP.
6.2.1.5
Succinate--CoA ligase (ADP-forming).
based on mapping to UniProt O19069
ATP + succinate + CoA = ADP + phosphate + succinyl-CoA.

UniProtKB Entries (1)

P53590
SUCB2_PIG
Sus scrofa
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

PDB Structure

PDB 1EUC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Phosphorylated and dephosphorylated structures of pig heart, GTP-specific succinyl-CoA synthetase.
Fraser, M.E., James, M.N., Bridger, W.A., Wolodko, W.T.
J.Mol.Biol.
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