CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Transcription initiation factor TFIID subunit

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P21675
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt P21675
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.

UniProtKB Entries (1)

P21675
TAF1_HUMAN
Homo sapiens
Transcription initiation factor TFIID subunit 1

PDB Structure

PDB 1EQF
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and function of a human TAFII250 double bromodomain module.
Jacobson, R.H., Ladurner, A.G., King, D.S., Tjian, R.
Science