CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.10 | Ribonuclease H-like superfamily/Ribonuclease H |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease H-like superfamily/Ribonuclease H |
| Functional Family | Ribonuclease HII |
Enzyme Information
| 3.1.26.4 |
Ribonuclease H.
based on mapping to UniProt Q57599
Endonucleolytic cleavage to 5'-phosphomonoester.
-!- Acts on RNA-DNA hybrids.
|
UniProtKB Entries (1)
| Q57599 |
RNH2_METJA
Methanocaldococcus jannaschii DSM 2661
Ribonuclease HII
|
PDB Structure
| PDB | 1EKE |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure of archaeal RNase HII: a homologue of human major RNase H
Structure
|