CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.960 | Lumazine/riboflavin synthase |
Domain Context
CATH Clusters
| Superfamily | Lumazine/riboflavin synthase |
| Functional Family | 6,7-dimethyl-8-ribityllumazine synthase |
Enzyme Information
| 2.5.1.78 |
6,7-dimethyl-8-ribityllumazine synthase.
based on mapping to UniProt P50861
1-deoxy-L-glycero-tetrulose 4-phosphate + 5-amino-6- (D-ribitylamino)uracil = 6,7-dimethyl-8-(D-ribityl)lumazine + 2 H(2)O + phosphate.
-!- Involved in riboflavin biosynthesis.
|
UniProtKB Entries (1)
| P50861 |
RIB4_YEAST
Saccharomyces cerevisiae S288C
6,7-dimethyl-8-ribityllumazine synthase
|
PDB Structure
| PDB | 1EJB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The atomic structure of pentameric lumazine synthase from Saccharomyces cerevisiae at 1.85 A resolution reveals the binding mode of a phosphonate intermediate analogue.
J.Mol.Biol.
|
