CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.2020
Functional Family Amidophosphoribosyltransferase

Enzyme Information

2.4.2.14
Amidophosphoribosyltransferase.
based on mapping to UniProt P0AG16
5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H(2)O.

UniProtKB Entries (1)

P0AG16
PUR1_ECOLI
Escherichia coli K-12
Amidophosphoribosyltransferase

PDB Structure

PDB 1ECC
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Coupled formation of an amidotransferase interdomain ammonia channel and a phosphoribosyltransferase active site.
Krahn, J.M., Kim, J.H., Burns, M.R., Parry, R.J., Zalkin, H., Smith, J.L.
Biochemistry