CATH Classification

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family Decarboxylase,orotidine phosphate

Enzyme Information

4.1.1.23
Orotidine-5'-phosphate decarboxylase.
based on mapping to UniProt P03962
Orotidine 5'-phosphate = UMP + CO(2).
-!- The enzyme from higher eukaryotes is identical with EC 2.4.2.10.

UniProtKB Entries (1)

P03962
PYRF_YEAST
Saccharomyces cerevisiae S288C
Orotidine 5'-phosphate decarboxylase

PDB Structure

PDB 1DQX
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Anatomy of a proficient enzyme: the structure of orotidine 5'-monophosphate decarboxylase in the presence and absence of a potential transition state analog.
Miller, B.G., Hassell, A.M., Wolfenden, R., Milburn, M.V., Short, S.A.
Proc.Natl.Acad.Sci.USA