CATH Classification

Domain Context

CATH Clusters

Superfamily MoaB/Mog-like domain
Functional Family Molybdopterin biosynthesis mog protein

Enzyme Information

2.7.7.75
Molybdopterin adenylyltransferase.
based on mapping to UniProt P0AF03
ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.
-!- Catalyzes the activation of molybdopterin for molybdenum insertion. -!- In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes molybdopterin molybdotransferase (EC 2.10.1.1). -!- The reaction requires a divalent cation such as Mg(2+) or Mn(2+). -!- Catalyzes the activation of molybdopterin for molybdenum insertion. -!- In eukaryotes, this reaction is catalyzed by the C-terminal domain of a fusion protein that also includes EC 2.10.1.1. -!- Formerly EC 2.7.7.n5.

UniProtKB Entries (1)

P0AF03
MOG_ECOLI
Escherichia coli K-12
Molybdopterin adenylyltransferase

PDB Structure

PDB 1DI7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of the gephyrin-related molybdenum cofactor biosynthesis protein MogA from Escherichia coli.
Liu, M.T., Wuebbens, M.M., Rajagopalan, K.V., Schindelin, H.
J.Biol.Chem.