CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Polymerase, chain B, domain 1
Functional Family DNA polymerase

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt Q7SIG7
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

Q7SIG7
DPOL_DESST
Desulfurococcus sp. Tok
DNA polymerase

PDB Structure

PDB 1D5A
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of an archaebacterial DNA polymerase.
Zhao, Y., Jeruzalmi, D., Moarefi, I., Leighton, L., Lasken, R., Kuriyan, J.
Structure Fold.Des.