CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.530.10
Functional Family Lytic murein transglycosylase B

Enzyme Information

4.2.2.n1
Peptidoglycan lytic exotransglycosylase.
based on mapping to UniProt P41052
Exolytic cleavage of the (1->4)-beta-glycosidic linkage between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (GlcNAc) residues in peptidoglycan, from either the reducing or the non-reducing ends of the peptidoglycan chains, with concomitant formation of a 1,6-anhydrobond in the MurNAc residue.

UniProtKB Entries (1)

P41052
MLTB_ECOLI
Escherichia coli K-12
Membrane-bound lytic murein transglycosylase B

PDB Structure

PDB 1D0M
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystallographic studies of the interactions of Escherichia coli lytic transglycosylase Slt35 with peptidoglycan.
van Asselt, E.J., Kalk, K.H., Dijkstra, B.W.
Biochemistry