CATH Classification

Domain Context

CATH Clusters

Superfamily Chitosanase, subunit A, domain 1
Functional Family

Enzyme Information

3.2.1.132
Chitosanase.
based on mapping to UniProt P33665
Endohydrolysis of beta-(1->4)-linkages between D-glucosamine residues in a partly acetylated chitosan.
-!- A whole spectrum of chitosanases are now known that can hydrolyze various types of links in chitosan. -!- The only constant property is the endohydrolysis of GlcN-GlcN links, which is common to all known chitosanases. -!- One known chitosanase is limited to this link recognition, while the majority can also recognize GlcN-GlcNAc links or GlcNAc-GlcN links but not both. -!- They also do not recognize GlcNAc-GlcNAc links in partly acetylated chitosan.

UniProtKB Entries (1)

P33665
CHIS_STRSN
Streptomyces sp. N174
Chitosanase

PDB Structure

PDB 1CHK
External Links
Method X-RAY DIFFRACTION
Organism Streptomyces
Primary Citation
X-ray structure of an anti-fungal chitosanase from streptomyces N174.
Marcotte, E.M., Monzingo, A.F., Ernst, S.R., Brzezinski, R., Robertus, J.D.
Nat.Struct.Biol.