CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family

Enzyme Information

2.4.2.1
Purine-nucleoside phosphorylase.
based on mapping to UniProt P81989
(1) Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. (2) Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.
-!- Specificity not completely determined. -!- Can also catalyze ribosyltransferase reactions of the type catalyzed by EC 2.4.2.5.

UniProtKB Entries (1)

P81989
PUNA_CELSP
Cellulomonas sp.
Purine nucleoside phosphorylase

PDB Structure

PDB 1C3X
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
Tebbe, J., Bzowska, A., Wielgus-Kutrowska, B., Schroder, W., Kazimierczuk, Z., Shugar, D., Saenger, W., Koellner, G.
J.Mol.Biol.