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1 keywords

CATH Domain 1bugB00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.1280 di-copper center containing domain from catechol oxidase
Homologous Superfamily 1.10.1280.10 Di-copper center containing domain from catechol oxidase

Domain Context

CATH Clusters

Superfamily Di-copper center containing domain from catechol oxidase
Functional Family Polyphenol oxidase, chloroplastic

Enzyme Information

1.10.3.1
Catechol oxidase.
based on mapping to UniProt Q9ZP19
2 catechol + O(2) = 2 1,2-benzoquinone + 2 H(2)O.
-!- A type 3 copper protein that catalyzes exclusively the oxidation of catechols (i.e., o-diphenols) to the corresponding o-quinones. -!- The enzyme also acts on a variety of substituted catechols. -!- It is different from tyrosinase, EC 1.14.18.1, which can catalyze both the monooxygenation of monophenols and the oxidation of catechols.

UniProtKB Entries (1)

Q9ZP19
PPO1_IPOBA
Ipomoea batatas
Polyphenol oxidase I, chloroplastic

PDB Structure

PDB 1BUG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a plant catechol oxidase containing a dicopper center.
Klabunde, T., Eicken, C., Sacchettini, J.C., Krebs, B.
Nat.Struct.Biol.
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