CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family

Enzyme Information

3.1.1.3
Triacylglycerol lipase.
based on mapping to UniProt P54318
Triacylglycerol + H(2)O = diacylglycerol + a carboxylate.
-!- The pancreatic enzyme acts only on an ester-water interface; the outer ester links are preferentially hydrolyzed.
3.1.1.26
Galactolipase.
based on mapping to UniProt P54318
1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H(2)O = 3-beta-D- galactosyl-sn-glycerol + 2 carboxylates.
-!- Also acts on 2,3-di-O-acyl-1-O-(6-O-alpha-D-galactosyl-beta-D- galactosyl)-D-glycerol, and phosphatidylcholine and other phospholipids.

UniProtKB Entries (1)

P54318
LIPR2_RAT
Rattus norvegicus
Pancreatic lipase-related protein 2

PDB Structure

PDB 1BU8
External Links
Method X-RAY DIFFRACTION
Organism Spodoptera
Primary Citation
Structure and activity of rat pancreatic lipase-related protein 2.
Roussel, A., Yang, Y., Ferrato, F., Verger, R., Cambillau, C., Lowe, M.
J.Biol.Chem.