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1 keywords

CATH Domain 1bthQ00

CATH Classification

Level CATH Code Description
Class 4 Few Secondary Structures
Architecture 4.10 Irregular
Topology 4.10.410 Factor Xa Inhibitor
Homologous Superfamily 4.10.410.10 Pancreatic trypsin inhibitor Kunitz domain

Domain Context

CATH Clusters

Superfamily Pancreatic trypsin inhibitor Kunitz domain
Functional Family Pancreatic trypsin inhibitor

Enzyme Information

UniProtKB Entries (2)

P00734
THRB_HUMAN
Homo sapiens
Prothrombin
P00974
BPT1_BOVIN
Bos taurus
Pancreatic trypsin inhibitor

PDB Structure

PDB 1BTH
External Links
Method X-RAY DIFFRACTION
Organism Mesocricetus
Primary Citation
The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin.
van de Locht, A., Bode, W., Huber, R., Le Bonniec, B.F., Stone, S.R., Esmon, C.T., Stubbs, M.T.
EMBO J.
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