CATH Domain 1bdmB02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.110	L-2-Hydroxyisocaproate Dehydrogenase; Chain A, domain 2
	3.90.110.10	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal

Domain Context

CATH Clusters

Superfamily	Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family	Malate dehydrogenase

Enzyme Information

1.1.1.37

Malate dehydrogenase.

based on mapping to UniProt P10584

(S)-malate + NAD(+) = oxaloacetate + NADH.

-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

MDH_THETH

Thermus thermophilus

Malate dehydrogenase

PDB Structure

PDB	1BDM
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus. Kelly, C.A., Nishiyama, M., Ohnishi, Y., Beppu, T., Birktoft, J.J. Biochemistry