CATH Classification

Domain Context

CATH Clusters

Superfamily 2.40.50.40
Functional Family C-C motif chemokine

Enzyme Information

UniProtKB Entries (1)

P10147
CCL3_HUMAN
Homo sapiens
C-C motif chemokine 3

PDB Structure

PDB 1B53
External Links
Method SOLUTION NMR
Organism Pichia
Primary Citation
Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants.
Czaplewski, L.G., McKeating, J., Craven, C.J., Higgins, L.D., Appay, V., Brown, A., Dudgeon, T., Howard, L.A., Meyers, T., Owen, J., Palan, S.R., Tan, P., Wilson, G., Woods, N.R., Heyworth, C.M., Lord, B.I., Brotherton, D., Christison, R., Craig, S., Cribbes, S., Edwards, R.M., Evans, S.J., Gilbert, R., Morgan, P., Randle, E., Schofield, N., Varley, P.G., Fisher, J., Waltho, J.P., Hunter, M.G.
J.Biol.Chem.