CATH Domain 1b43A02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.150	DNA polymerase; domain 1
	1.10.150.20	5' to 3' exonuclease, C-terminal subdomain

Domain Context

CATH Clusters

Superfamily	5' to 3' exonuclease, C-terminal subdomain
Functional Family	Flap endonuclease 1

Enzyme Information

3.1.-.-

Acting on ester bonds.

based on mapping to UniProt O93634

UniProtKB Entries (1)

FEN_PYRFU

Pyrococcus furiosus DSM 3638

Flap endonuclease 1

PDB Structure

PDB	1B43
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity. Hosfield, D.J., Mol, C.D., Shen, B., Tainer, J.A. Cell(Cambridge,Mass.)