CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P14555
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P14555
PA2GA_HUMAN
Homo sapiens
Phospholipase A2, membrane associated

PDB Structure

PDB 1AYP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A probe molecule composed of seventeen percent of total diffracting matter gives correct solutions in molecular replacement.
Oh, B.H.
Acta Crystallogr.,Sect.D