CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.10 | Deoxyribonuclease I; Chain A |
|
3.60.10.10 | Endonuclease/exonuclease/phosphatase |
Domain Context
CATH Clusters
| Superfamily | Endonuclease/exonuclease/phosphatase |
| Functional Family | Exodeoxyribonuclease III |
Enzyme Information
| 3.1.11.2 |
Exodeoxyribonuclease III.
based on mapping to UniProt P09030
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.
-!- Preference for double-stranded DNA. -!- Has endonucleolytic activity near apurinic sites on DNA. -!- Similar enzyme: Haemophilus influenzae exonuclease. -!- Formerly EC 3.1.4.27.
|
UniProtKB Entries (1)
| P09030 |
EX3_ECOLI
Escherichia coli K-12
Exodeoxyribonuclease III
|
PDB Structure
| PDB | 1AKO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Structure and function of the multifunctional DNA-repair enzyme exonuclease III.
Nature
|
