CATH Domain 1a5eA00

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.25	Alpha Horseshoe
	1.25.40	Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
	1.25.40.20	Ankyrin repeat-containing domain

Domain Context

CATH Clusters

Superfamily	Ankyrin repeat-containing domain
Functional Family	cyclin-dependent kinase 4 inhibitor B

Enzyme Information

UniProtKB Entries (1)

CDN2A_HUMAN

Homo sapiens

Cyclin-dependent kinase inhibitor 2A

PDB Structure

PDB	1A5E
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism	Escherichia
Primary Citation	Tumor suppressor p16INK4A: determination of solution structure and analyses of its interaction with cyclin-dependent kinase 4. Byeon, I.J., Li, J., Ericson, K., Selby, T.L., Tevelev, A., Kim, H.J., O'Maille, P., Tsai, M.D. Mol.Cell