CATH Domain 1a4eD00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.180	Catalase HpII, Chain A, domain 1
	2.40.180.10	Catalase core domain

Domain Context

CATH Clusters

Superfamily	Catalase core domain
Functional Family	Catalase

Enzyme Information

1.11.1.6

Catalase.

based on mapping to UniProt P15202

2 H(2)O(2) = O(2) + 2 H(2)O.

-!- A manganese protein containing Mn(III) in the resting state, which also belongs here, is often called pseudocatalase. -!- The enzymes from some organisms, such as Penicillium simplicissimum, can also act as a peroxidase (EC 1.11.1.7) for which several organic substances, especially ethanol, can act as a hydrogen donor. -!- Enzymes that exhibit both catalase and peroxidase activity belong under EC 1.11.1.21.

UniProtKB Entries (1)

P15202

CATA_YEAST

Saccharomyces cerevisiae S288C

Peroxisomal catalase A

PDB Structure

PDB	1A4E
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of catalase-A from Saccharomyces cerevisiae. Mate, M.J., Zamocky, M., Nykyri, L.M., Herzog, C., Alzari, P.M., Betzel, C., Koller, F., Fita, I. J.Mol.Biol.

Network disruptions