CATH Classification

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Acidic phospholipase A2

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P15445
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P15445
PA2A2_NAJNA
Naja naja
Acidic phospholipase A2 2

PDB Structure

PDB 1A3D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of two novel crystal forms of Naja naja naja phospholipase A2 lacking Ca2+ reveal trimeric packing.
Segelke, B.W., Nguyen, D., Chee, R., Xuong, N.H., Dennis, E.A.
J.Mol.Biol.