CATH Classification

Domain Context

CATH Clusters

Superfamily Peptidase C15, pyroglutamyl peptidase I-like
Functional Family

Enzyme Information

3.4.19.3
Pyroglutamyl-peptidase I.
based on mapping to UniProt O07883
Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.
-!- Removes 5-oxoproline from various penultimate amino acid residues except L-proline. -!- Inhibited by thiol-blocking reagents. -!- Belongs to peptidase family C15. -!- Formerly EC 3.4.11.8.

UniProtKB Entries (1)

O07883
PCP_THELN
Thermococcus litoralis DSM 5473
Pyrrolidone-carboxylate peptidase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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