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1 keywords

CATH Domain 1a2aA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.90 Phospholipase A2
Homologous Superfamily 1.20.90.10 Phospholipase A2 domain

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P14421
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P14421
PA2N_GLOHA
Gloydius halys
Neutral phospholipase A2 agkistrodotoxin

PDB Structure

PDB 1A2A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of agkistrodotoxin, a phospholipase A2-type presynaptic neurotoxin from agkistrodon halys pallas.
Tang, L., Zhou, Y.C., Lin, Z.J.
J.Mol.Biol.
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