PDB 6o39

PDB Information

PDB6O39
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Structure-guided design fine-tunes pharmacokinetics, tolerability, and antitumor profile of multispecific frizzled antibodies.
Raman, S., Beilschmidt, M., To, M., Lin, K., Lui, F., Jmeian, Y., Ng, M., Fernandez, M., Fu, Y., Mascall, K., Duque, A., Wang, X., Pan, G., Angers, S., Moffat, J., Sidhu, S.S., Magram, J., Sinclair, A.M., Fransson, J., Julien, J.P.
Proc. Natl. Acad. Sci. U.S.A.
HeaderSignaling Protein
Released2019-02-26
Resolution1.800
CATH Insert Date07 Apr, 2019

PDB Images (7)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2019 Chopped
B 07 Apr, 2019 Holding pen
C 07 Apr, 2019 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
6o39A01 08 Apr, 2019 2.60.40.10 Assigned
6o39A02 08 Apr, 2019 2.60.40.10 Assigned
6o39C00 08 Apr, 2019 1.10.2000.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q13467 FZD5_HUMAN Homo sapiens Frizzled-5