PDB 6ny4

PDB Information

PDB6NY4
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis.
Spergel, S.H., Mertzman, M.E., Kempson, J., Guo, J., Stachura, S., Haque, L., Lippy, J.S., Zhang, R.F., Galella, M., Pitt, S., Shen, G., Fura, A., Gillooly, K., McIntyre, K.W., Tang, V., Tokarski, J., Sack, J.S., Khan, J., Carter, P.H., Barrish, J.C., Nadler, S.G., Salter-Cid, L.M., Schieven, G.L., Wrobleski, S.T., Pitts, W.J.
Acs Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2019-02-11
Resolution2.330
CATH Insert Date26 May, 2019

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 May, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6ny4A01 27 May, 2019 3.30.200.20 Assigned
6ny4A02 27 May, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3