PDB 6nhf

PDB Information

PDB6NHF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.
Do, H.T., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2018-12-21
Resolution1.830
CATH Insert Date17 Mar, 2019

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped
C 17 Mar, 2019 Chopped
D 17 Mar, 2019 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6nhfA01 18 Mar, 2019 3.90.340.10 Assigned
6nhfA02 18 Mar, 2019 3.90.440.10 Assigned
6nhfA03 18 Mar, 2019 3.90.1230.10 Assigned
6nhfB01 18 Mar, 2019 3.90.340.10 Assigned
6nhfB02 18 Mar, 2019 3.90.440.10 Assigned
6nhfB03 18 Mar, 2019 3.90.1230.10 Assigned
6nhfC01 18 Mar, 2019 3.90.340.10 Assigned
6nhfC02 18 Mar, 2019 3.90.440.10 Assigned
6nhfC03 18 Mar, 2019 3.90.1230.10 Assigned
6nhfD01 18 Mar, 2019 3.90.340.10 Assigned
6nhfD02 18 Mar, 2019 3.90.440.10 Assigned
6nhfD03 18 Mar, 2019 3.90.1230.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial