PDB 6nh4

PDB Information

PDB6NH4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.
Do, H.T., Li, H., Chreifi, G., Poulos, T.L., Silverman, R.B.
J. Med. Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2018-12-21
Resolution2.270
CATH Insert Date17 Mar, 2019

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Mar, 2019 Chopped
B 17 Mar, 2019 Chopped
C 17 Mar, 2019 Chopped
D 17 Mar, 2019 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
6nh4A01 18 Mar, 2019 3.90.340.10 Assigned
6nh4A02 18 Mar, 2019 3.90.440.10 Assigned
6nh4A03 18 Mar, 2019 3.90.1230.10 Assigned
6nh4B01 18 Mar, 2019 3.90.340.10 Assigned
6nh4B02 18 Mar, 2019 3.90.440.10 Assigned
6nh4B03 18 Mar, 2019 3.90.1230.10 Assigned
6nh4C01 18 Mar, 2019 3.90.340.10 Assigned
6nh4C02 18 Mar, 2019 3.90.440.10 Assigned
6nh4C03 18 Mar, 2019 3.90.1230.10 Assigned
6nh4D01 18 Mar, 2019 3.90.340.10 Assigned
6nh4D02 18 Mar, 2019 3.90.440.10 Assigned
6nh4D03 18 Mar, 2019 3.90.1230.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial
P29474 NOS3_HUMAN Homo sapiens Nitric oxide synthase, endothelial