PDB Information

PDB6N1I
MethodELECTRON MICROSCOPY
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1.
Li, Y., Fu, T.M., Lu, A., Witt, K., Ruan, J., Shen, C., Wu, H.
Proc. Natl. Acad. Sci. U.S.A.
HeaderSignaling Protein
Released2018-11-08
Resolution3.580
CATH Insert Date16 Dec, 2018

PDB Images (33)

PDB Prints

PDB Chains (16)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped
C 16 Dec, 2018 Chopped
D 16 Dec, 2018 Chopped
E 16 Dec, 2018 Chopped
F 16 Dec, 2018 Chopped
G 16 Dec, 2018 Chopped
H 16 Dec, 2018 Chopped
I 16 Dec, 2018 Chopped
J 16 Dec, 2018 Chopped
K 16 Dec, 2018 Chopped
L 16 Dec, 2018 Chopped
M 16 Dec, 2018 Chopped
N 16 Dec, 2018 Chopped
O 16 Dec, 2018 Chopped
P 16 Dec, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6n1iA00 28 Feb, 2019 Holding pen
6n1iB00 28 Feb, 2019 Holding pen
6n1iC00 28 Feb, 2019 Holding pen
6n1iD00 28 Feb, 2019 Holding pen
6n1iE00 28 Feb, 2019 Holding pen
6n1iF00 28 Feb, 2019 Holding pen
6n1iG00 28 Feb, 2019 Holding pen
6n1iH00 28 Feb, 2019 Holding pen
6n1iI00 28 Feb, 2019 Holding pen
6n1iJ00 28 Feb, 2019 Holding pen
6n1iK00 28 Feb, 2019 Holding pen
6n1iL00 28 Feb, 2019 Holding pen
6n1iM00 28 Feb, 2019 Holding pen
6n1iN00 28 Feb, 2019 Holding pen
6n1iO00 28 Feb, 2019 Holding pen
6n1iP00 28 Feb, 2019 Holding pen

UniProtKB Entries (16)

Accession Gene ID Taxon Description
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4
Q9NPP4 NLRC4_HUMAN Homo sapiens NLR family CARD domain-containing protein 4