PDB 6mnl

PDB Information

PDB6MNL
MethodSOLUTION NMR
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Liu, J., Duan, Z., Guo, W., Zeng, L., Wu, Y., Chen, Y., Tai, F., Wang, Y., Lin, Y., Zhang, Q., He, Y., Deng, J., Stewart, R.L., Wang, C., Lin, P.C., Ghaffari, S., Evers, B.M., Liu, S., Zhou, M.M., Zhou, B.P., Shi, J.
Nat Commun
HeaderTranscription
Released2018-10-02
Resolution
CATH Insert Date16 Dec, 2018

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Rejected
B 16 Dec, 2018 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
6mnlB00 28 Feb, 2019 1.20.920.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O43524 FOXO3_HUMAN Homo sapiens Forkhead box protein O3
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4