PDB Information

PDB6IOK
MethodELECTRON MICROSCOPY
Host OrganismEscherichia coli
Gene SourcePseudomonas aeruginosa PAO1
Primary Citation
Structures of the wild-type MexAB-OprM tripartite pump reveal its complex formation and drug efflux mechanism.
Tsutsumi, K., Yonehara, R., Ishizaka-Ikeda, E., Miyazaki, N., Maeda, S., Iwasaki, K., Nakagawa, A., Yamashita, E.
Nat Commun
HeaderMembrane Protein
Released2018-10-30
Resolution3.640
CATH Insert Date07 Apr, 2019

PDB Images (19)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 07 Apr, 2019 Chopped
B 07 Apr, 2019 Chopped
C 07 Apr, 2019 Chopped
E 07 Apr, 2019 Holding pen
F 07 Apr, 2019 Holding pen
G 07 Apr, 2019 Holding pen
I 07 Apr, 2019 Holding pen
J 07 Apr, 2019 Holding pen
K 07 Apr, 2019 Holding pen
L 07 Apr, 2019 Holding pen
M 07 Apr, 2019 Write scan list
N 07 Apr, 2019 Holding pen

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
6iokA01 08 Apr, 2019 1.20.1600.10 Assigned
6iokA02 08 Apr, 2019 2.20.200.10 Assigned
6iokB01 08 Apr, 2019 1.20.1600.10 Assigned
6iokB02 08 Apr, 2019 2.20.200.10 Assigned
6iokC01 08 Apr, 2019 1.20.1600.10 Assigned
6iokC02 08 Apr, 2019 2.20.200.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
P52002 MEXB_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexB
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
Q51487 OPRM_PSEAE Pseudomonas aeruginosa PAO1 Outer membrane protein OprM
P52002 MEXB_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexB
Q51487 OPRM_PSEAE Pseudomonas aeruginosa PAO1 Outer membrane protein OprM
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
P52477 MEXA_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexA
Q51487 OPRM_PSEAE Pseudomonas aeruginosa PAO1 Outer membrane protein OprM
P52002 MEXB_PSEAE Pseudomonas aeruginosa PAO1 Multidrug resistance protein MexB