PDB 6i8s

PDB Links
Overview

PDB Information

PDB	6I8S
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1. Vousden, K.A., Lundqvist, T., Popovic, B., Naiman, B., Carruthers, A.M., Newton, P., Johnson, D.J.D., Pomowski, A., Wilkinson, T., Dufner, P., de Mendez, I., Mallinder, P.R., Murray, C., Strain, M., Connor, J., Murray, L.A., Sleeman, M.A., Lowe, D.C., Huntington, J.A., Vaughan, T.J. Sci Rep
Header	Blood Clotting
Released	2018-11-21
Resolution	2.900
CATH Insert Date	17 Feb, 2019

PDB Images (29)

6i8s

PDB 6i8s

6i8sA

PDB Chain 6i8sA

6i8sB

PDB Chain 6i8sB

6i8sC

PDB Chain 6i8sC

6i8sD

PDB Chain 6i8sD

6i8sE

PDB Chain 6i8sE

6i8sF

PDB Chain 6i8sF

6i8sG

PDB Chain 6i8sG

6i8sH

PDB Chain 6i8sH

6i8sI

PDB Chain 6i8sI

6i8sJ

PDB Chain 6i8sJ

6i8sK

PDB Chain 6i8sK

6i8sL

PDB Chain 6i8sL

6i8sA01

CATH Domain 6i8sA01

6i8sA02

CATH Domain 6i8sA02

6i8sB01

CATH Domain 6i8sB01

6i8sB02

CATH Domain 6i8sB02

6i8sC01

CATH Domain 6i8sC01

6i8sC02

CATH Domain 6i8sC02

6i8sD01

CATH Domain 6i8sD01

6i8sD02

CATH Domain 6i8sD02

6i8sI01

CATH Domain 6i8sI01

6i8sI02

CATH Domain 6i8sI02

6i8sJ01

CATH Domain 6i8sJ01

6i8sJ02

CATH Domain 6i8sJ02

6i8sK01

CATH Domain 6i8sK01

6i8sK02

CATH Domain 6i8sK02

6i8sL01

CATH Domain 6i8sL01

6i8sL02

CATH Domain 6i8sL02

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	17 Feb, 2019	Chopped
B	17 Feb, 2019	Chopped
C	17 Feb, 2019	Chopped
D	17 Feb, 2019	Chopped
E	17 Feb, 2019	Holding pen
F	17 Feb, 2019	Holding pen
G	17 Feb, 2019	Holding pen
H	17 Feb, 2019	Holding pen
I	17 Feb, 2019	Chopped
J	17 Feb, 2019	Chopped
K	17 Feb, 2019	Chopped
L	17 Feb, 2019	Chopped

CATH Domains (16)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6i8sA01	18 Feb, 2019	3.30.497.10	Assigned
6i8sA02	18 Feb, 2019	2.30.39.10	Assigned
6i8sB01	18 Feb, 2019	3.30.497.10	Assigned
6i8sB02	18 Feb, 2019	2.30.39.10	Assigned
6i8sC01	18 Feb, 2019	3.30.497.10	Assigned
6i8sC02	18 Feb, 2019	2.30.39.10	Assigned
6i8sD01	18 Feb, 2019	3.30.497.10	Assigned
6i8sD02	18 Feb, 2019	2.30.39.10	Assigned
6i8sI01	18 Feb, 2019	2.60.40.10	Assigned
6i8sI02	18 Feb, 2019	2.60.40.10	Assigned
6i8sJ01	18 Feb, 2019	2.60.40.10	Assigned
6i8sJ02	18 Feb, 2019	2.60.40.10	Assigned
6i8sK01	18 Feb, 2019	2.60.40.10	Assigned
6i8sK02	18 Feb, 2019	2.60.40.10	Assigned
6i8sL01	18 Feb, 2019	2.60.40.10	Assigned
6i8sL02	18 Feb, 2019	2.60.40.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P05121	PAI1_HUMAN	Homo sapiens	Plasminogen activator inhibitor 1
P05121	PAI1_HUMAN	Homo sapiens	Plasminogen activator inhibitor 1
P05121	PAI1_HUMAN	Homo sapiens	Plasminogen activator inhibitor 1
P05121	PAI1_HUMAN	Homo sapiens	Plasminogen activator inhibitor 1

Network disruptions