PDB 6i0z

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Overview

PDB Information

PDB	6I0Z
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents. Francis, S., Croft, D., Schuttelkopf, A.W., Parry, C., Pugliese, A., Cameron, K., Claydon, S., Drysdale, M., Gardner, C., Gohlke, A., Goodwin, G., Gray, C.H., Konczal, J., McDonald, L., Mezna, M., Pannifer, A., Paul, N.R., Machesky, L., McKinnon, H., Bower, J. Bioorg.Med.Chem.Lett.
Header	Structural Protein
Released	2018-10-27
Resolution	1.770
CATH Insert Date	03 Mar, 2019

PDB Images (11)

Image of CATH 6i0z

6i0z

PDB 6i0z

Image of CATH 6i0zA

6i0zA

PDB Chain 6i0zA

Image of CATH 6i0zB

6i0zB

PDB Chain 6i0zB

Image of CATH 6i0zA01

6i0zA01

CATH Domain 6i0zA01

Image of CATH 6i0zA02

6i0zA02

CATH Domain 6i0zA02

Image of CATH 6i0zA03

6i0zA03

CATH Domain 6i0zA03

Image of CATH 6i0zA04

6i0zA04

CATH Domain 6i0zA04

Image of CATH 6i0zB01

6i0zB01

CATH Domain 6i0zB01

Image of CATH 6i0zB02

6i0zB02

CATH Domain 6i0zB02

Image of CATH 6i0zB03

6i0zB03

CATH Domain 6i0zB03

Image of CATH 6i0zB04

6i0zB04

CATH Domain 6i0zB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	03 Mar, 2019	Chopped
B	03 Mar, 2019	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6i0zA01	04 Mar, 2019	2.80.10.50	Assigned
6i0zA02	04 Mar, 2019	2.80.10.50	Assigned
6i0zA03	04 Mar, 2019	2.80.10.50	Assigned
6i0zA04	04 Mar, 2019	2.80.10.50	Assigned
6i0zB01	04 Mar, 2019	2.80.10.50	Assigned
6i0zB02	04 Mar, 2019	2.80.10.50	Assigned
6i0zB03	04 Mar, 2019	2.80.10.50	Assigned
6i0zB04	04 Mar, 2019	2.80.10.50	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q16658	FSCN1_HUMAN	Homo sapiens	Fascin
Q16658	FSCN1_HUMAN	Homo sapiens	Fascin