PDB 6i04

PDB Links
Overview

PDB Information

PDB	6I04
Method	X-RAY DIFFRACTION
Host Organism	Homo sapiens
Gene Source	Homo sapiens
Primary Citation	MM-131, a bispecific anti-Met/EpCAM mAb, inhibits HGF-dependent and HGF-independent Met signaling through concurrent binding to EpCAM. Casaletto, J.B., Geddie, M.L., Abu-Yousif, A.O., Masson, K., Fulgham, A., Boudot, A., Maiwald, T., Kearns, J.D., Kohli, N., Su, S., Razlog, M., Raue, A., Kalra, A., Hakansson, M., Logan, D.T., Welin, M., Chattopadhyay, S., Harms, B.D., Nielsen, U.B., Schoeberl, B., Lugovskoy, A.A., MacBeath, G. Proc.Natl.Acad.Sci.USA
Header	Immune System
Released	2018-10-25
Resolution	3.100
CATH Insert Date	17 Mar, 2019

PDB Images (11)

Image of CATH 6i04

6i04

PDB 6i04

Image of CATH 6i04A

6i04A

PDB Chain 6i04A

Image of CATH 6i04B

6i04B

PDB Chain 6i04B

Image of CATH 6i04C

6i04C

PDB Chain 6i04C

Image of CATH 6i04D

6i04D

PDB Chain 6i04D

Image of CATH 6i04H

6i04H

PDB Chain 6i04H

Image of CATH 6i04L

6i04L

PDB Chain 6i04L

Image of CATH 6i04D01

6i04D01

CATH Domain 6i04D01

Image of CATH 6i04D02

6i04D02

CATH Domain 6i04D02

Image of CATH 6i04L01

6i04L01

CATH Domain 6i04L01

Image of CATH 6i04L02

6i04L02

CATH Domain 6i04L02

PDB Prints

PDB Chains (6)

Chain ID	Date inserted into CATH	CATH Status
A	17 Mar, 2019	Holding pen
B	17 Mar, 2019	Write scan list
C	17 Mar, 2019	Holding pen
D	17 Mar, 2019	Chopped
H	17 Mar, 2019	Holding pen
L	17 Mar, 2019	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
6i04D01	18 Mar, 2019	2.60.40.10	Assigned
6i04D02	18 Mar, 2019	2.60.40.10	Assigned
6i04L01	18 Mar, 2019	2.60.40.10	Assigned
6i04L02	18 Mar, 2019	2.60.40.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P08581	MET_HUMAN	Homo sapiens	Hepatocyte growth factor receptor
P08581	MET_HUMAN	Homo sapiens	Hepatocyte growth factor receptor