PDB Information

PDB6HTI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceSchistosoma mansoni
Primary Citation
Characterization of Histone Deacetylase 8 (HDAC8) Selective Inhibition Reveals Specific Active Site Structural and Functional Determinants.
Marek, M., Shaik, T.B., Heimburg, T., Chakrabarti, A., Lancelot, J., Ramos-Morales, E., Da Veiga, C., Kalinin, D., Melesina, J., Robaa, D., Schmidtkunz, K., Suzuki, T., Holl, R., Ennifar, E., Pierce, R.J., Jung, M., Sippl, W., Romier, C.
J. Med. Chem.
HeaderHydrolase
Released2018-10-04
Resolution1.690
CATH Insert Date16 Dec, 2018

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2018 Chopped
B 16 Dec, 2018 Chopped
C 16 Dec, 2018 Chopped
D 16 Dec, 2018 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
6htiA00 28 Feb, 2019 3.40.800.20 Assigned
6htiB00 28 Feb, 2019 3.40.800.20 Assigned
6htiC00 28 Feb, 2019 3.40.800.20 Assigned
6htiD00 28 Feb, 2019 3.40.800.20 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
A5H660 A5H660_SCHMA Schistosoma mansoni Histone deacetylase 8
A5H660 A5H660_SCHMA Schistosoma mansoni Histone deacetylase 8
A5H660 A5H660_SCHMA Schistosoma mansoni Histone deacetylase 8
A5H660 A5H660_SCHMA Schistosoma mansoni Histone deacetylase 8