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PDB 6hrp

PDB Information

PDB6HRP
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A potent seven-membered cyclic BTK (Bruton's tyrosine Kinase) chiral inhibitor conceived by structure-based drug design to lock its bioactive conformation.
Lopez-Tapia, F., Lou, Y., Brotherton-Pleiss, C., Kuglstatter, A., So, S.S., Kondru, R.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2018-09-28
Resolution1.120
CATH Insert Date24 Mar, 2019

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Mar, 2019 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6hrpA01 25 Mar, 2019 3.30.200.20 Assigned
6hrpA02 25 Mar, 2019 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK
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