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PDB Information
| PDB | 6GMR |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation |
Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
Lucas, X., Van Molle, I., Ciulli, A.
J. Med. Chem.
|
| Header | Ligase |
| Released | 2018-05-28 |
| Resolution | 1.750 |
| CATH Insert Date | 12 Aug, 2018 |
PDB Images (9)
6gmrB00
CATH Domain 6gmrB00
6gmrC00
CATH Domain 6gmrC00
6gmrV01
CATH Domain 6gmrV01
6gmrV02
CATH Domain 6gmrV02
PDB Chains (4)
CATH Domains (4)
UniProtKB Entries (4)
| Accession |
Gene ID |
Taxon |
Description |
| Q15369 |
ELOC_HUMAN |
Homo sapiens |
Elongin-C |
| P40337 |
VHL_HUMAN |
Homo sapiens |
von Hippel-Lindau disease tumor suppressor |
| Q15370 |
ELOB_HUMAN |
Homo sapiens |
Elongin-B |
| Q16665 |
HIF1A_HUMAN |
Homo sapiens |
Hypoxia-inducible factor 1-alpha |