PDB 6gmr
PDB Information
| PDB | 6GMR |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
J. Med. Chem.
|
| Header | Ligase |
| Released | 2018-05-28 |
| Resolution | 1.750 |
| CATH Insert Date | 12 Aug, 2018 |
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| B | 12 Aug, 2018 | Chopped |
| C | 12 Aug, 2018 | Chopped |
| H | 12 Aug, 2018 | Rejected |
| V | 12 Aug, 2018 | Chopped |
CATH Domains (4)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6gmrB00 | 13 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmrC00 | 13 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmrV01 | 13 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmrV02 | 13 Aug, 2018 | 1.10.750.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q16665 | HIF1A_HUMAN | Homo sapiens | Hypoxia-inducible factor 1-alpha |
