PDB 6gmq
PDB Information
| PDB | 6GMQ |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | Surface Probing by Fragment-Based Screening and Computational Methods Identifies Ligandable Pockets on the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase.
J. Med. Chem.
|
| Header | Oncoprotein |
| Released | 2018-05-28 |
| Resolution | 2.760 |
| CATH Insert Date | 26 Aug, 2018 |
PDB Images (29)
6gmq
PDB 6gmq
6gmqA
PDB Chain 6gmqA
6gmqB
PDB Chain 6gmqB
6gmqC
PDB Chain 6gmqC
6gmqD
PDB Chain 6gmqD
6gmqE
PDB Chain 6gmqE
6gmqF
PDB Chain 6gmqF
6gmqG
PDB Chain 6gmqG
6gmqH
PDB Chain 6gmqH
6gmqI
PDB Chain 6gmqI
6gmqJ
PDB Chain 6gmqJ
6gmqK
PDB Chain 6gmqK
6gmqL
PDB Chain 6gmqL
6gmqA00
CATH Domain 6gmqA00
6gmqB00
CATH Domain 6gmqB00
6gmqC01
CATH Domain 6gmqC01
6gmqC02
CATH Domain 6gmqC02
6gmqD00
CATH Domain 6gmqD00
6gmqE00
CATH Domain 6gmqE00
6gmqF01
CATH Domain 6gmqF01
6gmqF02
CATH Domain 6gmqF02
6gmqG00
CATH Domain 6gmqG00
6gmqH00
CATH Domain 6gmqH00
6gmqI01
CATH Domain 6gmqI01
6gmqI02
CATH Domain 6gmqI02
6gmqJ00
CATH Domain 6gmqJ00
6gmqK00
CATH Domain 6gmqK00
6gmqL01
CATH Domain 6gmqL01
6gmqL02
CATH Domain 6gmqL02
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 26 Aug, 2018 | Chopped |
| B | 26 Aug, 2018 | Chopped |
| C | 26 Aug, 2018 | Chopped |
| D | 26 Aug, 2018 | Chopped |
| E | 26 Aug, 2018 | Chopped |
| F | 26 Aug, 2018 | Chopped |
| G | 26 Aug, 2018 | Chopped |
| H | 26 Aug, 2018 | Chopped |
| I | 26 Aug, 2018 | Chopped |
| J | 26 Aug, 2018 | Chopped |
| K | 26 Aug, 2018 | Chopped |
| L | 26 Aug, 2018 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6gmqA00 | 27 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmqB00 | 27 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmqC01 | 27 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmqC02 | 27 Aug, 2018 | 1.10.750.10 | Assigned |
| 6gmqD00 | 27 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmqE00 | 27 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmqF01 | 27 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmqF02 | 27 Aug, 2018 | 1.10.750.10 | Assigned |
| 6gmqG00 | 27 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmqH00 | 27 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmqI01 | 27 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmqI02 | 27 Aug, 2018 | 1.10.750.10 | Assigned |
| 6gmqJ00 | 27 Aug, 2018 | 3.10.20.90 | Assigned |
| 6gmqK00 | 27 Aug, 2018 | 3.30.710.10 | Assigned |
| 6gmqL01 | 27 Aug, 2018 | 2.60.40.780 | Assigned |
| 6gmqL02 | 27 Aug, 2018 | 1.10.750.10 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
