PDB 6gl8

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Overview

PDB Information

PDB	6GL8
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth. Casara, P., Davidson, J., Claperon, A., Le Toumelin-Braizat, G., Vogler, M., Bruno, A., Chanrion, M., Lysiak-Auvity, G., Le Diguarher, T., Starck, J.B., Chen, I., Whitehead, N., Graham, C., Matassova, N., Dokurno, P., Pedder, C., Wang, Y., Qiu, S., Girard, A.M., Schneider, E., Grave, F., Studeny, A., Guasconi, G., Rocchetti, F., Maiga, S., Henlin, J.M., Colland, F., Kraus-Berthier, L., Le Gouill, S., Dyer, M.J.S., Hubbard, R., Wood, M., Amiot, M., Cohen, G.M., Hickman, J.A., Morris, E., Murray, J., Geneste, O. Oncotarget
Header	Apoptosis
Released	2018-05-23
Resolution	1.400
CATH Insert Date	16 Dec, 2018

PDB Images (2)

Image of CATH 6gl8

6gl8

PDB 6gl8

Image of CATH 6gl8A

6gl8A

PDB Chain 6gl8A

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	16 Dec, 2018	Holding pen

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q07817	B2CL1_HUMAN	Homo sapiens	Bcl-2-like protein 1
P10415	BCL2_HUMAN	Homo sapiens	Apoptosis regulator Bcl-2