PDB 6gfz

PDB Information

PDB6GFZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation.
Testa, A., Lucas, X., Castro, G.V., Chan, K.H., Wright, J.E., Runcie, A.C., Gadd, M.S., Harrison, W.T.A., Ko, E.J., Fletcher, D., Ciulli, A.
J. Am. Chem. Soc.
HeaderLigase
Released2018-05-02
Resolution2.300
CATH Insert Date16 Jul, 2018

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 16 Jul, 2018 Chopped
B 16 Jul, 2018 Chopped
C 16 Jul, 2018 Chopped
D 16 Jul, 2018 Chopped
E 16 Jul, 2018 Chopped
F 16 Jul, 2018 Chopped
G 16 Jul, 2018 Chopped
H 16 Jul, 2018 Chopped
I 16 Jul, 2018 Chopped
J 16 Jul, 2018 Chopped
K 16 Jul, 2018 Chopped
L 16 Jul, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6gfzA00 19 Jul, 2018 3.10.20.90 Assigned
6gfzB00 19 Jul, 2018 3.30.710.10 Assigned
6gfzC01 19 Jul, 2018 2.60.40.780 Assigned
6gfzC02 19 Jul, 2018 1.10.750.10 Assigned
6gfzD00 19 Jul, 2018 3.10.20.90 Assigned
6gfzE00 19 Jul, 2018 3.30.710.10 Assigned
6gfzF01 19 Jul, 2018 2.60.40.780 Assigned
6gfzF02 19 Jul, 2018 1.10.750.10 Assigned
6gfzG00 19 Jul, 2018 3.10.20.90 Assigned
6gfzH00 19 Jul, 2018 3.30.710.10 Assigned
6gfzI01 19 Jul, 2018 2.60.40.780 Assigned
6gfzI02 19 Jul, 2018 1.10.750.10 Assigned
6gfzJ00 19 Jul, 2018 3.10.20.90 Assigned
6gfzK00 19 Jul, 2018 3.30.710.10 Assigned
6gfzL01 19 Jul, 2018 2.60.40.780 Assigned
6gfzL02 19 Jul, 2018 1.10.750.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C