PDB 6gfy

PDB Information

PDB6GFY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
3-Fluoro-4-hydroxyprolines: Synthesis, Conformational Analysis, and Stereoselective Recognition by the VHL E3 Ubiquitin Ligase for Targeted Protein Degradation.
Testa, A., Lucas, X., Castro, G.V., Chan, K.H., Wright, J.E., Runcie, A.C., Gadd, M.S., Harrison, W.T.A., Ko, E.J., Fletcher, D., Ciulli, A.
J. Am. Chem. Soc.
HeaderLigase
Released2018-05-02
Resolution2.700
CATH Insert Date16 Jul, 2018

PDB Images (29)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 16 Jul, 2018 Chopped
B 16 Jul, 2018 Chopped
C 16 Jul, 2018 Chopped
D 16 Jul, 2018 Chopped
E 16 Jul, 2018 Chopped
F 16 Jul, 2018 Chopped
G 16 Jul, 2018 Chopped
H 16 Jul, 2018 Chopped
I 16 Jul, 2018 Chopped
J 16 Jul, 2018 Chopped
K 16 Jul, 2018 Chopped
L 16 Jul, 2018 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
6gfyA00 19 Jul, 2018 3.10.20.90 Assigned
6gfyB00 19 Jul, 2018 3.30.710.10 Assigned
6gfyC01 19 Jul, 2018 2.60.40.780 Assigned
6gfyC02 19 Jul, 2018 1.10.750.10 Assigned
6gfyD00 19 Jul, 2018 3.10.20.90 Assigned
6gfyE00 19 Jul, 2018 3.30.710.10 Assigned
6gfyF01 19 Jul, 2018 2.60.40.780 Assigned
6gfyF02 19 Jul, 2018 1.10.750.10 Assigned
6gfyG00 19 Jul, 2018 3.10.20.90 Assigned
6gfyH00 19 Jul, 2018 3.30.710.10 Assigned
6gfyI01 19 Jul, 2018 2.60.40.780 Assigned
6gfyI02 19 Jul, 2018 1.10.750.10 Assigned
6gfyJ00 19 Jul, 2018 3.10.20.90 Assigned
6gfyK00 19 Jul, 2018 3.30.710.10 Assigned
6gfyL01 19 Jul, 2018 2.60.40.780 Assigned
6gfyL02 19 Jul, 2018 1.10.750.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor
Q15369 ELOC_HUMAN Homo sapiens Elongin-C
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
Q15370 ELOB_HUMAN Homo sapiens Elongin-B
P40337 VHL_HUMAN Homo sapiens von Hippel-Lindau disease tumor suppressor