PDB 6fmk
PDB Information
| PDB | 6FMK |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21(DE3) |
| Gene Source | Homo sapiens |
| Primary Citation | Thioamide substitution to probe the hydroxyproline recognition of VHL ligands.
Bioorg. Med. Chem.
|
| Header | Ligase |
| Released | 2018-01-31 |
| Resolution | 2.750 |
| CATH Insert Date | 03 Jun, 2018 |
PDB Images (29)
6fmk
PDB 6fmk
6fmkA
PDB Chain 6fmkA
6fmkB
PDB Chain 6fmkB
6fmkC
PDB Chain 6fmkC
6fmkD
PDB Chain 6fmkD
6fmkE
PDB Chain 6fmkE
6fmkF
PDB Chain 6fmkF
6fmkG
PDB Chain 6fmkG
6fmkH
PDB Chain 6fmkH
6fmkI
PDB Chain 6fmkI
6fmkJ
PDB Chain 6fmkJ
6fmkK
PDB Chain 6fmkK
6fmkL
PDB Chain 6fmkL
6fmkA00
CATH Domain 6fmkA00
6fmkB00
CATH Domain 6fmkB00
6fmkC01
CATH Domain 6fmkC01
6fmkC02
CATH Domain 6fmkC02
6fmkD00
CATH Domain 6fmkD00
6fmkE00
CATH Domain 6fmkE00
6fmkF01
CATH Domain 6fmkF01
6fmkF02
CATH Domain 6fmkF02
6fmkG00
CATH Domain 6fmkG00
6fmkH00
CATH Domain 6fmkH00
6fmkI01
CATH Domain 6fmkI01
6fmkI02
CATH Domain 6fmkI02
6fmkJ00
CATH Domain 6fmkJ00
6fmkK00
CATH Domain 6fmkK00
6fmkL01
CATH Domain 6fmkL01
6fmkL02
CATH Domain 6fmkL02
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 03 Jun, 2018 | Chopped |
| B | 03 Jun, 2018 | Chopped |
| C | 03 Jun, 2018 | Chopped |
| D | 03 Jun, 2018 | Chopped |
| E | 03 Jun, 2018 | Chopped |
| F | 03 Jun, 2018 | Chopped |
| G | 03 Jun, 2018 | Chopped |
| H | 03 Jun, 2018 | Chopped |
| I | 03 Jun, 2018 | Chopped |
| J | 03 Jun, 2018 | Chopped |
| K | 03 Jun, 2018 | Chopped |
| L | 03 Jun, 2018 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6fmkA00 | 29 Jun, 2018 | 3.10.20.90 | Assigned |
| 6fmkB00 | 29 Jun, 2018 | 3.30.710.10 | Assigned |
| 6fmkC01 | 29 Jun, 2018 | 2.60.40.780 | Assigned |
| 6fmkC02 | 29 Jun, 2018 | 1.10.750.10 | Assigned |
| 6fmkD00 | 29 Jun, 2018 | 3.10.20.90 | Assigned |
| 6fmkE00 | 29 Jun, 2018 | 3.30.710.10 | Assigned |
| 6fmkF01 | 29 Jun, 2018 | 2.60.40.780 | Assigned |
| 6fmkF02 | 29 Jun, 2018 | 1.10.750.10 | Assigned |
| 6fmkG00 | 29 Jun, 2018 | 3.10.20.90 | Assigned |
| 6fmkH00 | 29 Jun, 2018 | 3.30.710.10 | Assigned |
| 6fmkI01 | 29 Jun, 2018 | 2.60.40.780 | Assigned |
| 6fmkI02 | 29 Jun, 2018 | 1.10.750.10 | Assigned |
| 6fmkJ00 | 29 Jun, 2018 | 3.10.20.90 | Assigned |
| 6fmkK00 | 29 Jun, 2018 | 3.30.710.10 | Assigned |
| 6fmkL01 | 29 Jun, 2018 | 2.60.40.780 | Assigned |
| 6fmkL02 | 29 Jun, 2018 | 1.10.750.10 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
