PDB 6fmj
PDB Information
| PDB | 6FMJ |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21(DE3) |
| Gene Source | Homo sapiens |
| Primary Citation | Thioamide substitution to probe the hydroxyproline recognition of VHL ligands.
Bioorg. Med. Chem.
|
| Header | Ligase |
| Released | 2018-01-31 |
| Resolution | 2.450 |
| CATH Insert Date | 03 Jun, 2018 |
PDB Images (29)
6fmj
PDB 6fmj
6fmjA
PDB Chain 6fmjA
6fmjB
PDB Chain 6fmjB
6fmjC
PDB Chain 6fmjC
6fmjD
PDB Chain 6fmjD
6fmjE
PDB Chain 6fmjE
6fmjF
PDB Chain 6fmjF
6fmjG
PDB Chain 6fmjG
6fmjH
PDB Chain 6fmjH
6fmjI
PDB Chain 6fmjI
6fmjJ
PDB Chain 6fmjJ
6fmjK
PDB Chain 6fmjK
6fmjL
PDB Chain 6fmjL
6fmjA00
CATH Domain 6fmjA00
6fmjB00
CATH Domain 6fmjB00
6fmjC01
CATH Domain 6fmjC01
6fmjC02
CATH Domain 6fmjC02
6fmjD00
CATH Domain 6fmjD00
6fmjE00
CATH Domain 6fmjE00
6fmjF01
CATH Domain 6fmjF01
6fmjF02
CATH Domain 6fmjF02
6fmjG00
CATH Domain 6fmjG00
6fmjH00
CATH Domain 6fmjH00
6fmjI01
CATH Domain 6fmjI01
6fmjI02
CATH Domain 6fmjI02
6fmjJ00
CATH Domain 6fmjJ00
6fmjK00
CATH Domain 6fmjK00
6fmjL01
CATH Domain 6fmjL01
6fmjL02
CATH Domain 6fmjL02
PDB Prints
PDB Chains (12)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 03 Jun, 2018 | Chopped |
| B | 03 Jun, 2018 | Chopped |
| C | 03 Jun, 2018 | Chopped |
| D | 03 Jun, 2018 | Chopped |
| E | 03 Jun, 2018 | Chopped |
| F | 03 Jun, 2018 | Chopped |
| G | 03 Jun, 2018 | Chopped |
| H | 03 Jun, 2018 | Chopped |
| I | 03 Jun, 2018 | Chopped |
| J | 03 Jun, 2018 | Chopped |
| K | 03 Jun, 2018 | Chopped |
| L | 03 Jun, 2018 | Chopped |
CATH Domains (16)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 6fmjA00 | 29 Jun, 2018 | 3.10.20.90 | Assigned |
| 6fmjB00 | 29 Jun, 2018 | 3.30.710.10 | Assigned |
| 6fmjC01 | 29 Jun, 2018 | 2.60.40.780 | Assigned |
| 6fmjC02 | 29 Jun, 2018 | 1.10.750.10 | Assigned |
| 6fmjD00 | 29 Jun, 2018 | 3.10.20.90 | Assigned |
| 6fmjE00 | 29 Jun, 2018 | 3.30.710.10 | Assigned |
| 6fmjF01 | 29 Jun, 2018 | 2.60.40.780 | Assigned |
| 6fmjF02 | 29 Jun, 2018 | 1.10.750.10 | Assigned |
| 6fmjG00 | 29 Jun, 2018 | 3.10.20.90 | Assigned |
| 6fmjH00 | 29 Jun, 2018 | 3.30.710.10 | Assigned |
| 6fmjI01 | 29 Jun, 2018 | 2.60.40.780 | Assigned |
| 6fmjI02 | 29 Jun, 2018 | 1.10.750.10 | Assigned |
| 6fmjJ00 | 29 Jun, 2018 | 3.10.20.90 | Assigned |
| 6fmjK00 | 29 Jun, 2018 | 3.30.710.10 | Assigned |
| 6fmjL01 | 29 Jun, 2018 | 2.60.40.780 | Assigned |
| 6fmjL02 | 29 Jun, 2018 | 1.10.750.10 | Assigned |
UniProtKB Entries (12)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
| Q15370 | ELOB_HUMAN | Homo sapiens | Elongin-B |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| P40337 | VHL_HUMAN | Homo sapiens | von Hippel-Lindau disease tumor suppressor |
| Q15369 | ELOC_HUMAN | Homo sapiens | Elongin-C |
