A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.
Ladds, M.J.G.W., van Leeuwen, I.M.M., Drummond, C.J., Chu, S., Healy, A.R., Popova, G., Pastor Fernandez, A., Mollick, T., Darekar, S., Sedimbi, S.K., Nekulova, M., Sachweh, M.C.C., Campbell, J., Higgins, M., Tuck, C., Popa, M., Safont, M.M., Gelebart, P., Fandalyuk, Z., Thompson, A.M., Svensson, R., Gustavsson, A.L., Johansson, L., Farnegardh, K., Yngve, U., Saleh, A., Haraldsson, M., D'Hollander, A.C.A., Franco, M., Zhao, Y., Hakansson, M., Walse, B., Larsson, K., Peat, E.M., Pelechano, V., Lunec, J., Vojtesek, B., Carmena, M., Earnshaw, W.C., McCarthy, A.R., Westwood, N.J., Arsenian-Henriksson, M., Lane, D.P., Bhatia, R., McCormack, E., Lain, S.
Nat Commun