PDB Information

Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
How a beta-D-glucoside side chain enhances binding affinity to thrombin of inhibitors bearing 2-chlorothiophene as P1 moiety: crystallography, fragment deconstruction study, and evaluation of antithrombotic properties.
Belviso, B.D., Caliandro, R., de Candia, M., Zaetta, G., Lopopolo, G., Incampo, F., Colucci, M., Altomare, C.D.
J. Med. Chem.
HeaderBlood Clotting
CATH Insert Date07 Jan, 2018

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 07 Jan, 2018 Chopped
I 07 Jan, 2018 Rejected
L 07 Jan, 2018 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
6eo9H01 11 Jan, 2018 Holding pen
6eo9H02 11 Jan, 2018 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P09945 HIRV2_HIRME Hirudo medicinalis Hirudin variant-2
P00734 THRB_HUMAN Homo sapiens Prothrombin